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Chemical structure of TWIK-1/TREK-1-IN-3

GC71090

TWIK-1/TREK-1-IN-3

Also known as (2S)-1-(4-pyrrolidin-1-ylpiperidin-1-yl)-3-[4-(trifluoromethyl)phenoxy]propan-2-ol

TWIK-1/TREK-1-IN-3 (compound 2h) is an inhibitor of TWIK-related potassium channel (Potassium Channel) TREK-1

ChemicalCAS1440532-33-1MW372.43FormulaC19H27F3N2O2
CAS number
1440532-33-1
Molecular weight
372.43
Formula
C19H27F3N2O2
Solubility
DMSO : 25 mg/mL (67·13 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
CGWZNOCWGMKTOS-KRWDZBQOSA-N
Catalogue number
GC71090
Brand
GLPBIO
Computed properties PubChem CID 118131592 · XLogP 3.3 · TPSA 35.9 Ų · H-bond donors 1
XLogP
3.3
TPSA
35.9 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
26

SMILES C1CCN(C1)C2CCN(CC2)C[C@@H](COC3=CC=C(C=C3)C(F)(F)F)O

Computed descriptors from PubChem (CID 118131592), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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