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Chemical structure of Sortilin antagonist 1

GC71039

Sortilin antagonist 1

Also known as (2S)-5,5-dimethyl-2-[(6-phenoxypyridine-3-carbonyl)amino]hexanoic acid

Sortilin antagonist 1 (compound 44) is a sortilin antagonist with an IC50 value of 20 nM for inhibiting Neurotensin (NTS) binds to sortilin

ChemicalCAS2691846-93-0MW356.42FormulaC20H24N2O4
CAS number
2691846-93-0
Molecular weight
356.42
Formula
C20H24N2O4
InChIKey
OWESOSHRVQOBOS-INIZCTEOSA-N
Catalogue number
GC71039
Brand
GLPBIO
Computed properties PubChem CID 162653277 · XLogP 4.1 · TPSA 88.5 Ų · H-bond donors 2
XLogP
4.1
TPSA
88.5 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
8
Heavy atoms
26

SMILES CC(C)(C)CC[C@@H](C(=O)O)NC(=O)C1=CN=C(C=C1)OC2=CC=CC=C2

Computed descriptors from PubChem (CID 162653277), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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