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Chemical structure of Glucocorticoid receptor agonist-2

GC71030

Glucocorticoid receptor agonist-2

Also known as (1S,2S,4R,6R,8S,9S,11S,12R,13S,19S)-6-[4-(3-aminophenoxy)phenyl]-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one

Glucocorticoid receptor agonist-2 (compound 21) is an glucocorticoid receptor agonist with an IC50 value of 6·6 nM

ChemicalCAS2166378-92-1MW607.64FormulaC34H35F2NO7
CAS number
2166378-92-1
Molecular weight
607.64
Formula
C34H35F2NO7
Solubility
DMSO ： 12·5 mg/mL (20·57 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
LCDCPIOGHJGDBP-APTODLHGSA-N
Catalogue number
GC71030
Brand
GLPBIO
Computed properties PubChem CID 134491916 · XLogP 4.2 · TPSA 128 Ų · H-bond donors 3
XLogP
4.2
TPSA
128 Ų
H-bond donors
3
H-bond acceptors
10
Rotatable bonds
5
Heavy atoms
44

SMILES C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@@H]4[C@]2(O[C@@H](O4)C5=CC=C(C=C5)OC6=CC=CC(=C6)N)C(=O)CO)C[C@@H](C7=CC(=O)C=C[C@@]73C)F)F)O

Computed descriptors from PubChem (CID 134491916), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.