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Chemical structure of PM-43I

GC71016

PM-43I

Also known as [[difluoro-[4-[(E)-4-[[(3S)-1-[2-(N-methylanilino)-2-oxoethyl]-2-oxoazepan-3-yl]amino]-4-oxobut-2-en-2-yl]phenyl]methyl]-(2,2-dimethylpropanoyloxymethoxy)phosphoryl]oxymethyl 2,2-dimethylpropanoate

PM-43I is a potent STAT6 inhibitor and can reduce STAT6 phosphorylation level

ChemicalCAS1637532-77-4MW777.79FormulaC38H50F2N3O10P
CAS number
1637532-77-4
Molecular weight
777.79
Formula
C38H50F2N3O10P
Solubility
DMSO : 35 mg/mL (45·00 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
MUOJHRIQZPVHNP-ZLMUDAIHSA-N
Catalogue number
GC71016
Brand
GLPBIO
Computed properties PubChem CID 154731124 · XLogP 6.3 · TPSA 158 Ų · H-bond donors 1
XLogP
6.3
TPSA
158 Ų
H-bond donors
1
H-bond acceptors
12
Rotatable bonds
18
Heavy atoms
54

SMILES C/C(=C\C(=O)N[C@H]1CCCCN(C1=O)CC(=O)N(C)C2=CC=CC=C2)/C3=CC=C(C=C3)C(F)(F)P(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C

Computed descriptors from PubChem (CID 154731124), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.