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Chemical structure of Emprumapimod

GC70927

Emprumapimod

Also known as N-[(2S)-1-amino-4-(dimethylamino)-1-oxobutan-2-yl]-5-(2,4-difluorophenoxy)-1-(2-methylpropyl)indazole-6-carboxamide

Emprumapimod (PF-07265803) is a potent, orally active and selective inhibitor of p38α MAPK directly inhibits LPS-induced IL-6 production from RPMI-8226 cell (IC50=100 pM)

ChemicalCAS765914-60-1MW473.52FormulaC24H29F2N5O3
CAS number
765914-60-1
Molecular weight
473.52
Formula
C24H29F2N5O3
Solubility
DMSO ： 100 mg/mL (211·18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
JOOOJNJPZINWHM-IBGZPJMESA-N
Catalogue number
GC70927
Brand
GLPBIO
Computed properties PubChem CID 67411502 · XLogP 3.2 · TPSA 102 Ų · H-bond donors 2
XLogP
3.2
TPSA
102 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
10
Heavy atoms
34

SMILES CC(C)CN1C2=CC(=C(C=C2C=N1)OC3=C(C=C(C=C3)F)F)C(=O)N[C@@H](CCN(C)C)C(=O)N

Computed descriptors from PubChem (CID 67411502), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.