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Chemical structure of (R)-Safinamide

GC70848

(R)-Safinamide

Also known as (2R)-2-[[4-[(3-fluorophenyl)methoxy]phenyl]methylamino]propanamide

(R)-Safinamide, the enantiomer of safinamide , can inhibit MAO-B with an IC50 value of 0·45 μM

ChemicalCAS174756-44-6MW302.34FormulaC17H19FN2O2
CAS number
174756-44-6
Molecular weight
302.34
Formula
C17H19FN2O2
Solubility
DMSO : ≥ 125 mg/mL (413·44 mM)
InChIKey
NEMGRZFTLSKBAP-GFCCVEGCSA-N
Catalogue number
GC70848
Brand
GLPBIO
Computed properties PubChem CID 5487407 · XLogP 2.2 · TPSA 64.4 Ų · H-bond donors 2
XLogP
2.2
TPSA
64.4 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
7
Heavy atoms
22

SMILES C[C@H](C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F

Computed descriptors from PubChem (CID 5487407), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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