Loading...
Chemical structure of Tilpisertib

GC70785

Tilpisertib

Also known as 6-[[(S)-[1-(1-bicyclo[1.1.1]pentanyl)triazol-4-yl]-(2-methyl-1-oxoisoquinolin-5-yl)methyl]amino]-8-chloro-4-(2,2-dimethylpropylamino)quinoline-3-carbonitrile

Tilpisertib (GS-4875) is a serine/threonine kinase inhibitor (WO2017007689)

ChemicalCAS2065153-41-3MW593.12FormulaC33H33ClN8O
CAS number
2065153-41-3
Molecular weight
593.12
Formula
C33H33ClN8O
Solubility
DMSO ： 125 mg/mL (210·75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
VFGSKBLZRDRHOI-ZAGPDIDGSA-N
Catalogue number
GC70785
Brand
GLPBIO
Computed properties PubChem CID 124181541 · XLogP 6 · TPSA 112 Ų · H-bond donors 2
XLogP
6
TPSA
112 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
8
Heavy atoms
43

SMILES CC(C)(C)CNC1=C2C=C(C=C(C2=NC=C1C#N)Cl)N[C@@H](C3=CC=CC4=C3C=CN(C4=O)C)C5=CN(N=N5)C67CC(C6)C7

Computed descriptors from PubChem (CID 124181541), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.