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Chemical structure of A1AT modulator 1

GC70714

A1AT modulator 1

Also known as N-[(1S,2R)-1-(3-fluoro-2-methylphenyl)-1-hydroxypentan-2-yl]-2-oxo-1,3-dihydroindole-4-carboxamide

A1AT modulator 1 is a potent inhibitor of Z ai-antitrypsin polymerisation with a pIC50 value of 8·3

ChemicalCAS2406205-61-4MW370.42FormulaC21H23FN2O3
CAS number
2406205-61-4
Molecular weight
370.42
Formula
C21H23FN2O3
Solubility
DMSO ： 100 mg/mL (269·96 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
MSZBLPYPBQYDNI-QUCCMNQESA-N
Catalogue number
GC70714
Brand
GLPBIO
Computed properties PubChem CID 146285629 · XLogP 2.7 · TPSA 78.4 Ų · H-bond donors 3
XLogP
2.7
TPSA
78.4 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
6
Heavy atoms
27

SMILES CCC[C@H]([C@H](C1=C(C(=CC=C1)F)C)O)NC(=O)C2=C3CC(=O)NC3=CC=C2

Computed descriptors from PubChem (CID 146285629), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.