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Chemical structure of RH01386

GC70570

RH01386

Also known as 4-cyclohexyl-2-[2-nitro-4-(trifluoromethyl)phenyl]sulfanyl-6-oxo-1H-pyrimidine-5-carbonitrile

RH01386 is a small molecule that can prevent endoplasmic reticulum stress (ERS)-induced β cell dysfunction and death, and inhibits proapoptotic gene expression

ChemicalCAS301177-36-6MW424.4FormulaC18H15F3N4O3S
CAS number
301177-36-6
Molecular weight
424.4
Formula
C18H15F3N4O3S
Solubility
DMSO ： 100 mg/mL (235·63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
BVWCKDMNROTYMZ-UHFFFAOYSA-N
Catalogue number
GC70570
Brand
GLPBIO
Computed properties PubChem CID 135441816 · XLogP 4.6 · TPSA 136 Ų · H-bond donors 1
XLogP
4.6
TPSA
136 Ų
H-bond donors
1
H-bond acceptors
9
Rotatable bonds
3
Heavy atoms
29

SMILES C1CCC(CC1)C2=C(C(=O)NC(=N2)SC3=C(C=C(C=C3)C(F)(F)F)[N+](=O)[O-])C#N

Computed descriptors from PubChem (CID 135441816), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.