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Chemical structure of SMN-C2

GC70566

SMN-C2

Also known as 3-(6,8-dimethylimidazo[1,2-a]pyrazin-2-yl)-7-[(3S)-4-ethyl-3-methylpiperazin-1-yl]chromen-2-one

SMN-C2, an analog of RG-7916, is a selective modulator of SMN2 gene splicing that acts by binding SMN2 pre-mRNA, thereby increasing far upstream element binding protein 1 (FUBP1) and KH-spliced RNA binding Protein affinity regulator protein (KHSRP) to the SMN2 pre-mRNA complex

ChemicalCAS1446311-56-3MW417.5FormulaC24H27N5O2
CAS number
1446311-56-3
Molecular weight
417.5
Formula
C24H27N5O2
Solubility
DMSO ： 7·14 mg/mL (17·10 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
PETSCYDXCUXNIW-INIZCTEOSA-N
Catalogue number
GC70566
Brand
GLPBIO
Computed properties PubChem CID 89657166 · XLogP 3.9 · TPSA 63 Ų · H-bond donors 0
XLogP
3.9
TPSA
63 Ų
H-bond donors
0
H-bond acceptors
6
Rotatable bonds
3
Heavy atoms
31

SMILES CCN1CCN(C[C@@H]1C)C2=CC3=C(C=C2)C=C(C(=O)O3)C4=CN5C=C(N=C(C5=N4)C)C

Computed descriptors from PubChem (CID 89657166), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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