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Chemical structure of QL-X-138

GC70565

QL-X-138

Also known as N-[2-methyl-5-[2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1-yl]phenyl]prop-2-enamide

QL-X-138 is a potent and selective BTK/MNK dual kinase inhibitor, exhibits covalent binding to BTK and non-covalent binding to MNK

ChemicalCAS1469988-63-3MW421.45FormulaC25H19N5O2
CAS number
1469988-63-3
Molecular weight
421.45
Formula
C25H19N5O2
Solubility
DMSO ： 25 mg/mL (59·32 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
JMVDIGHUQAXWIE-UHFFFAOYSA-N
Catalogue number
GC70565
Brand
GLPBIO
Computed properties PubChem CID 73707530 · XLogP 3.4 · TPSA 91 Ų · H-bond donors 2
XLogP
3.4
TPSA
91 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
32

SMILES CC1=C(C=C(C=C1)N2C(=O)C=CC3=CN=C4C=CC(=CC4=C32)C5=CNN=C5)NC(=O)C=C

Computed descriptors from PubChem (CID 73707530), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.