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Chemical structure of Ampreloxetine TFA

GC70476

Ampreloxetine TFA

Also known as 2,2,2-trifluoroacetic acid;4-[2-[(2,4,6-trifluorophenoxy)methyl]phenyl]piperidine

Ampreloxetine (TD-9855) TFA is a potent and orally active norepinephrine (NE) and serotonin 5-HT inhibitor

ChemicalCAS1227056-85-0MW435.36FormulaC20H19F6NO3
CAS number
1227056-85-0
Molecular weight
435.36
Formula
C20H19F6NO3
Solubility
DMSO : 100 mg/mL (229·69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
MDURTULDKWJPAB-UHFFFAOYSA-N
Catalogue number
GC70476
Brand
GLPBIO
Computed properties PubChem CID 134280433 · TPSA 58.6 Ų · H-bond donors 2 · H-bond acceptors 10
TPSA
58.6 Ų
H-bond donors
2
H-bond acceptors
10
Rotatable bonds
4
Heavy atoms
30

SMILES C1CNCCC1C2=CC=CC=C2COC3=C(C=C(C=C3F)F)F.C(=O)(C(F)(F)F)O

Computed descriptors from PubChem (CID 134280433), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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