Loading...
Chemical structure of 6bK TFA

GC70313

6bK TFA

Also known as (3R,6S,9S,12E,16S)-9-(4-aminobutyl)-3-[(4-benzoylphenyl)methyl]-6-(cyclohexylmethyl)-2,5,8,11,14-pentaoxo-1,4,7,10,15-pentazacycloicos-12-ene-16-carboxamide;2,2,2-trifluoroacetic acid

6bK TFA is a potent and selective insulin degrading enzyme (IDE) inhibitor with an IC50 value of 50 nM

ChemicalCAS1774353-12-6MW871.94FormulaC43H56F3N7O9
CAS number
1774353-12-6
Molecular weight
871.94
Formula
C43H56F3N7O9
Solubility
DMSO ： 100 mg/mL (114·69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
YYZNAMZJUJTYPS-GNVBVUGKSA-N
Catalogue number
GC70313
Brand
GLPBIO
Computed properties PubChem CID 164512670 · TPSA 269 Ų · H-bond donors 8 · H-bond acceptors 13
TPSA
269 Ų
H-bond donors
8
H-bond acceptors
13
Rotatable bonds
11
Heavy atoms
62

SMILES C1CCC(CC1)C[C@H]2C(=O)N[C@@H](C(=O)NCCCC[C@H](NC(=O)/C=C/C(=O)N[C@H](C(=O)N2)CCCCN)C(=O)N)CC3=CC=C(C=C3)C(=O)C4=CC=CC=C4.C(=O)(C(F)(F)F)O

Computed descriptors from PubChem (CID 164512670), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.