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Chemical structure of Ritlecitinib tosylate

GC70211

Ritlecitinib tosylate

Also known as 4-methylbenzenesulfonic acid;1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one

Ritlecitinib tosylate is an orally active and selective JAK3 inhibitor with an IC50 of 33·1 nM

ChemicalCAS2192215-81-7MW457.55FormulaC22H27N5O4S
CAS number
2192215-81-7
Molecular weight
457.55
Formula
C22H27N5O4S
Solubility
DMSO ： 83·33 mg/mL (182·12 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
YOZLVAFWYLSRRN-VZXYPILPSA-N
Catalogue number
GC70211
Brand
GLPBIO
Computed properties PubChem CID 145722621 · TPSA 137 Ų · H-bond donors 3 · H-bond acceptors 7
TPSA
137 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
32

SMILES C[C@H]1CC[C@H](CN1C(=O)C=C)NC2=NC=NC3=C2C=CN3.CC1=CC=C(C=C1)S(=O)(=O)O

Computed descriptors from PubChem (CID 145722621), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.