Loading...
Chemical structure of WDR5-0102

GC70141

WDR5-0102

Also known as 2-chloro-N-[2-(4-methylpiperazin-1-yl)-5-nitrophenyl]benzamide

WDR5-0102 is an inhibitor that targets WDR5-MLL1 (with a Kdis of 7 μM and a Kd of 4 μM)· It inhibits the activity of MLL1 but does not inhibit human H3K4 methyltransferase SETD7 or six other HMTs: G9a, EHMT1, SUV39H2, SETD8, PRMT3, and PRMT5

ChemicalCAS824960-50-1MW374.82FormulaC18H19ClN4O3
CAS number
824960-50-1
Molecular weight
374.82
Formula
C18H19ClN4O3
Solubility
DMSO ： 50 mg/mL (133·40 mM; ultrasonic and warming and heat to 60°C)
InChIKey
WOGZFCMBPXJNFI-UHFFFAOYSA-N
Catalogue number
GC70141
Brand
GLPBIO
Computed properties PubChem CID 2965974 · XLogP 3.1 · TPSA 81.4 Ų · H-bond donors 1
XLogP
3.1
TPSA
81.4 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
3
Heavy atoms
26

SMILES CN1CCN(CC1)C2=C(C=C(C=C2)[N+](=O)[O-])NC(=O)C3=CC=CC=C3Cl

Computed descriptors from PubChem (CID 2965974), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.