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Chemical structure of W1131

GC70140

W1131

Also known as 5-nitro-N-[4-[7-(1,2,3,6-tetrahydropyridin-4-yl)imidazo[1,2-a]pyridin-3-yl]phenyl]furan-2-carboxamide

W1131 is an effective STAT3 inhibitor that can induce ferroptosis· W1131 inhibits cancer progression in gastric cancer subcutaneous xenograft models, organoid models, and PDX models· W1131 effectively reduces chemoresistance of cancer cells to 5-FU· W1131 regulates cell cycle, DNA damage response, and oxidative phosphorylation pathways including the IL6-JAK-STAT3 pathway and ferroptosis pathway

ChemicalCAS2740522-79-4MW429.43FormulaC23H19N5O4
CAS number
2740522-79-4
Molecular weight
429.43
Formula
C23H19N5O4
InChIKey
CMVDOFFRPTYZID-UHFFFAOYSA-N
Catalogue number
GC70140
Brand
GLPBIO
Computed properties PubChem CID 162371933 · XLogP 3.6 · TPSA 117 Ų · H-bond donors 2
XLogP
3.6
TPSA
117 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
32

SMILES C1CNCC=C1C2=CC3=NC=C(N3C=C2)C4=CC=C(C=C4)NC(=O)C5=CC=C(O5)[N+](=O)[O-]

Computed descriptors from PubChem (CID 162371933), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.