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Chemical structure of UCM-1306

GC70086

UCM-1306

Also known as [4-[2-(fluoromethoxy)phenyl]phenyl]-imino-methyl-oxo-lambda6-sulfane

UCM-1306 is an orally effective positive allosteric modulator (PAM) of the human dopamine D1 receptor· UCM-1306 increases the maximal effect of endogenous dopamine (DA) in both human and mouse D1 receptors· It not only improves motor symptoms but also addresses key comorbid cognitive impairments associated with long-term Parkinson's disease (PD)

ChemicalCAS2258608-78-3MW279.33FormulaC14H14FNO2S
CAS number
2258608-78-3
Molecular weight
279.33
Formula
C14H14FNO2S
Solubility
DMSO : 50 mg/mL (179·00 mM; Need ultrasonic)
InChIKey
VCSBOASGFYJGGT-UHFFFAOYSA-N
Catalogue number
GC70086
Brand
GLPBIO
Computed properties PubChem CID 137364063 · XLogP 4.5 · TPSA 58.5 Ų · H-bond donors 1
XLogP
4.5
TPSA
58.5 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
19

SMILES CS(=N)(=O)C1=CC=C(C=C1)C2=CC=CC=C2OCF

Computed descriptors from PubChem (CID 137364063), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
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