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Chemical structure of TSPO ligand-1

GC70072

TSPO ligand-1

Also known as 2-oxo-2-(2-phenyl-1H-indol-3-yl)acetyl chloride

TSPO ligand-1 is a ligand for AUTAC4 and can be used to synthesize PROTACs· TSPO ligand-1 is a mitochondrial outer membrane transmembrane domain protein that can bind to AUTAC4, regulate mitophagy (autophagy of mitochondria), and promote targeted mitochondrial renewal· TSPO ligand-1 can also participate in the transport of cholesterol from the outer membrane to the inner membrane of mitochondria, serving as a sensitive biomarker for brain injury and neurodegeneration

ChemicalCAS4560-08-1MW283.71FormulaC16H10ClNO2
CAS number
4560-08-1
Molecular weight
283.71
Formula
C16H10ClNO2
Solubility
DMSO ： 125 mg/mL (440·59 mM; Need ultrasonic)
InChIKey
DREHVYWKTXGDBS-UHFFFAOYSA-N
Catalogue number
GC70072
Brand
GLPBIO
Computed properties PubChem CID 12589400 · XLogP 4.1 · TPSA 49.9 Ų · H-bond donors 1
XLogP
4.1
TPSA
49.9 Ų
H-bond donors
1
H-bond acceptors
2
Rotatable bonds
3
Heavy atoms
20

SMILES C1=CC=C(C=C1)C2=C(C3=CC=CC=C3N2)C(=O)C(=O)Cl

Computed descriptors from PubChem (CID 12589400), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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