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Chemical structure of Topoisomerase I inhibitor 8

GC70044

Topoisomerase I inhibitor 8

Also known as (10S)-10-ethyl-18-fluoro-10-hydroxy-19-methyl-8-oxa-4,15-diazahexacyclo[14.7.1.02,14.04,13.06,11.020,24]tetracosa-1,6(11),12,14,16,18,20(24)-heptaene-5,9-dione

Topoisomerase I inhibitor 8 is a potent inhibitor of topoisomerase I· It is a camptothecin analogue and has toxicity against tumor cells

ChemicalCAS210346-40-0MW420.43FormulaC24H21FN2O4
CAS number
210346-40-0
Molecular weight
420.43
Formula
C24H21FN2O4
InChIKey
YLGVBUAQTQSHCD-DEOSSOPVSA-N
Catalogue number
GC70044
Brand
GLPBIO
Computed properties PubChem CID 10025127 · XLogP 2 · TPSA 79.7 Ų · H-bond donors 1
XLogP
2
TPSA
79.7 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
1
Heavy atoms
31

SMILES CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C5CCCC6=C5C(=CC(=C6C)F)N=C4C3=C2)O

Computed descriptors from PubChem (CID 10025127), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.