GC70013
Teprotumumab
Teprotumumab is a human monoclonal antibody that blocks the insulin-like growth factor-1 receptor (IGF-1R)· Teprotumumab binds to the ligand-binding domain of the extracellular alpha subunit of IGF-1R· It inhibits the actions of TSH and IGF-1 in fibroblasts· Teprotumumab reduces the expression of IL-6 and IL-8, which are dependent on TSH, as well as phosphorylation of Akt· It can be used for research related to thyroid-associated eye disease
ChemicalCAS1036734-93-6
- CAS number
- 1036734-93-6
- Molecular weight
- —
- Formula
- —
- Catalogue number
- GC70013
- Brand
- GLPBIO
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il