GC70002
TDP1 Inhibitor-2
Also known as 7-[(2,6-dichlorophenyl)methoxy]-4-(2-oxochromen-3-yl)chromen-2-one
TDP1 Inhibitor-2 (compound 5) is an effective inhibitor of TDP1 (tyrosyl-DNA phosphodiesterase 1), with an IC50 of 99 nM· TDP1 Inhibitor-2 can also inhibit SCAN1 (spinocerebellar ataxia with axonal neuropathy), with an IC50 of 3·5 μM
ChemicalCAS859142-95-3MW465.28FormulaC25H14Cl2O5
- CAS number
- 859142-95-3
- Molecular weight
- 465.28
- Formula
- C25H14Cl2O5
- Solubility
- DMSO ： 8·33 mg/mL (17·90 mM; ultrasonic and warming and heat to 80°C)
- InChIKey
- QEOYHBDGERTIQV-UHFFFAOYSA-N
- Catalogue number
- GC70002
- Brand
- GLPBIO
Computed properties PubChem CID 1767837 · XLogP 5.8 · TPSA 61.8 Ų · H-bond donors 0
- XLogP
- 5.8
- TPSA
- 61.8 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Rotatable bonds
- 4
- Heavy atoms
- 32
SMILES C1=CC=C2C(=C1)C=C(C(=O)O2)C3=CC(=O)OC4=C3C=CC(=C4)OCC5=C(C=CC=C5Cl)Cl
Computed descriptors from PubChem (CID 1767837), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il