GC69991
Pifusertib hydrochloride
Also known as 3-amino-1-methyl-3-[4-(5-phenyl-8-oxa-3,6,12-triazatricyclo[7.4.0.02,6]trideca-1(9),2,4,10,12-pentaen-4-yl)phenyl]cyclobutan-1-ol;hydrochloride
Pifusertib (TAS-117) hydrochloride is an effective, selective, and orally active isoform Akt inhibitor (with IC50 values of 4·8, 1·6, and 44 nM for Akt1, 2, and 3 respectively)· Pifusertib hydrochloride stimulates anti-myeloma activity and enhances lethal endoplasmic reticulum stress induced by proteasome inhibition· Pifusertib hydrochloride induces apoptosis and autophagy in cells
- CAS number
- 2930090-28-9
- Molecular weight
- 460.96
- Formula
- C26H25ClN4O2
- Solubility
- DMSO ： 62·5 mg/mL (135·59 mM; ultrasonic and warming and heat to 60°C)
- InChIKey
- JPKYUPVHSPWRNX-UHFFFAOYSA-N
- Catalogue number
- GC69991
- Brand
- GLPBIO
Computed properties PubChem CID 156178303 · TPSA 86.2 Ų · H-bond donors 3 · H-bond acceptors 5
- TPSA
- 86.2 Ų
- H-bond donors
- 3
- H-bond acceptors
- 5
- Rotatable bonds
- 3
- Heavy atoms
- 33
SMILES CC1(CC(C1)(C2=CC=C(C=C2)C3=C(N4COC5=C(C4=N3)C=NC=C5)C6=CC=CC=C6)N)O.Cl
Computed descriptors from PubChem (CID 156178303), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il