
GC69977
(S)-Veliflapon
Also known as (2S)-2-cyclopentyl-2-[4-(quinolin-2-ylmethoxy)phenyl]acetic acid
(S)-Veliflapon ((S)-BAY X 1005) is an orally active leukotriene biosynthesis and 5-lipoxygenase activating protein (FLAP) inhibitor· It inhibits the formation of leukotriene B4 (LTB4) in rat, mouse, and human white blood cells with IC50 values of 0·026 μM, 0·039 μM, and 0·22 μM respectively· (S)-Veliflapon exhibits enantioselectivity in human whole blood
ChemicalCAS128253-32-7MW361.43FormulaC23H23NO3
- CAS number
- 128253-32-7
- Molecular weight
- 361.43
- Formula
- C23H23NO3
- Solubility
- DMSO : 100 mg/mL (276·68 mM; Need ultrasonic)
- InChIKey
- ZEYYDOLCHFETHQ-QFIPXVFZSA-N
- Catalogue number
- GC69977
- Brand
- GLPBIO
Computed properties PubChem CID 22860799 · XLogP 5.4 · TPSA 59.4 Ų · H-bond donors 1
- XLogP
- 5.4
- TPSA
- 59.4 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Rotatable bonds
- 6
- Heavy atoms
- 27
SMILES C1CCC(C1)[C@@H](C2=CC=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)C(=O)O
Computed descriptors from PubChem (CID 22860799), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il