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Chemical structure of (S)-Veliflapon

GC69977

(S)-Veliflapon

Also known as (2S)-2-cyclopentyl-2-[4-(quinolin-2-ylmethoxy)phenyl]acetic acid

(S)-Veliflapon ((S)-BAY X 1005) is an orally active leukotriene biosynthesis and 5-lipoxygenase activating protein (FLAP) inhibitor· It inhibits the formation of leukotriene B4 (LTB4) in rat, mouse, and human white blood cells with IC50 values of 0·026 μM, 0·039 μM, and 0·22 μM respectively· (S)-Veliflapon exhibits enantioselectivity in human whole blood

ChemicalCAS128253-32-7MW361.43FormulaC23H23NO3
CAS number
128253-32-7
Molecular weight
361.43
Formula
C23H23NO3
Solubility
DMSO : 100 mg/mL (276·68 mM; Need ultrasonic)
InChIKey
ZEYYDOLCHFETHQ-QFIPXVFZSA-N
Catalogue number
GC69977
Brand
GLPBIO
Computed properties PubChem CID 22860799 · XLogP 5.4 · TPSA 59.4 Ų · H-bond donors 1
XLogP
5.4
TPSA
59.4 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
6
Heavy atoms
27

SMILES C1CCC(C1)[C@@H](C2=CC=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)C(=O)O

Computed descriptors from PubChem (CID 22860799), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.