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Chemical structure of Serine Hydrolase inhibitor-21

GC69878

Serine Hydrolase inhibitor-21

Also known as 5-(phenothiazine-10-carbonyl)-1H-pyridin-2-one

Serine Hydrolase inhibitor-21 (compound 8) is a pyridine and a serine hydrolase inhibitor with a Ki of 429 nM for BuChE· It has potential for use in Alzheimer's disease research

ChemicalCAS366448-34-2MW320.37FormulaC18H12N2O2S
CAS number
366448-34-2
Molecular weight
320.37
Formula
C18H12N2O2S
Solubility
DMSO : 12 mg/mL (37·46 mM; ultrasonic and warming and heat to 60°C)
InChIKey
FRWOZZSGXZOOSM-UHFFFAOYSA-N
Catalogue number
GC69878
Brand
GLPBIO
Computed properties PubChem CID 9836747 · XLogP 2.6 · TPSA 74.7 Ų · H-bond donors 1
XLogP
2.6
TPSA
74.7 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
1
Heavy atoms
23

SMILES C1=CC=C2C(=C1)N(C3=CC=CC=C3S2)C(=O)C4=CNC(=O)C=C4

Computed descriptors from PubChem (CID 9836747), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.