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Chemical structure of Sampatrilat

GC69856

Sampatrilat

Also known as (2S)-2-[[[(2S)-6-amino-2-(methanesulfonamido)hexanoyl]amino]methyl]-3-[1-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]carbamoyl]cyclopentyl]propanoic acid

Sampatrilat (UK-81252) is a potent orally active vasopeptidase inhibitor that inhibits both angiotensin-converting enzyme (ACE) and neutral endopeptidase (NEP)· Sampatrilat has 12·4 times greater inhibition of C-domain ACE (Ki=13·8 nM) compared to N-domain ACE (Ki=171·9 nM)· Sampatrilat (UK-81252) can be used for research related to chronic heart failure and blood pressure regulation

ChemicalCAS129981-36-8MW584.68FormulaC26H40N4O9S
CAS number
129981-36-8
Molecular weight
584.68
Formula
C26H40N4O9S
Solubility
DMSO ： 100 mg/mL (171·03 mM; Need ultrasonic)
InChIKey
LPUDGHQMOAHMMF-JBACZVJFSA-N
Catalogue number
GC69856
Brand
GLPBIO
Computed properties PubChem CID 6324648 · XLogP -1.6 · TPSA 234 Ų · H-bond donors 7
XLogP
-1.6
TPSA
234 Ų
H-bond donors
7
H-bond acceptors
11
Rotatable bonds
17
Heavy atoms
40

SMILES CS(=O)(=O)N[C@@H](CCCCN)C(=O)NC[C@H](CC1(CCCC1)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)O)C(=O)O

Computed descriptors from PubChem (CID 6324648), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.