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Chemical structure of Ruserontinib

GC69843

Ruserontinib

Also known as 2-N-[4-(4-methylpiperazin-1-yl)phenyl]-9-propan-2-yl-8-N-pyridin-3-ylpurine-2,8-diamine

Ruserontinib (SKLB1028) is an orally active inhibitor of EGFR, FLT3, and Abl kinases with an IC50 value of 55 nM against human FLT3· It has anti-tumor activity

ChemicalCAS1350544-93-2MW443.55FormulaC24H29N9
CAS number
1350544-93-2
Molecular weight
443.55
Formula
C24H29N9
Solubility
DMSO ： 250 mg/mL (563·63 mM; Need ultrasonic)
InChIKey
WSOHOUHPUOAXIN-UHFFFAOYSA-N
Catalogue number
GC69843
Brand
GLPBIO
Computed properties PubChem CID 54760385 · XLogP 3.4 · TPSA 87 Ų · H-bond donors 2
XLogP
3.4
TPSA
87 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
6
Heavy atoms
33

SMILES CC(C)N1C2=NC(=NC=C2N=C1NC3=CN=CC=C3)NC4=CC=C(C=C4)N5CCN(CC5)C

Computed descriptors from PubChem (CID 54760385), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.