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Chemical structure of Rosuvastatin Sodium

GC69833

Rosuvastatin Sodium

Also known as sodium (E,3R,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate

Rosuvastatin Sodium is a competitive inhibitor of HMG-CoA reductase (HMGCR), with an IC50 of 11 nM· It effectively blocks hERG currents, with an IC50 of 195 nM· Rosuvastatin Sodium reduces the expression of mature hERG and the interaction between heat shock protein 70 (Hsp70) and hERG protein· Rosuvastatin Sodium effectively lowers levels of low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein

ChemicalCAS147098-18-8MW503.52FormulaC22H27FN3NaO6S
CAS number
147098-18-8
Molecular weight
503.52
Formula
C22H27FN3NaO6S
Solubility
DMSO ： 250 mg/mL (496·50 mM; Need ultrasonic)
InChIKey
RGEBGDYYHAFODH-DHMAKVBVSA-M
Catalogue number
GC69833
Brand
GLPBIO
Computed properties PubChem CID 23684378 · TPSA 152 Ų · H-bond donors 2 · H-bond acceptors 10
TPSA
152 Ų
H-bond donors
2
H-bond acceptors
10
Rotatable bonds
10
Heavy atoms
34

SMILES CC(C)C1=NC(=NC(=C1/C=C/[C@H](C[C@H](CC(=O)[O-])O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C.[Na+]

Computed descriptors from PubChem (CID 23684378), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.