GC69730
PP-C8
PP-C8 is an effective selective PROTAC CDK12-Cyclin K degrader· PP-C8 induces degradation of CDK12-Cyclin K with DC50 values of 416 and 412 nM, respectively· PP-C8 exhibits highly efficient synergistic anti-proliferative effects with PARP inhibitors in triple-negative breast cancer (TNBC)
ChemicalMW866.94FormulaC43H51FN12O7
- CAS number
- —
- Molecular weight
- 866.94
- Formula
- C43H51FN12O7
- Solubility
- DMSO ： 100 mg/mL (115·35 mM; ultrasonic and warming and heat to 60°C)
- Catalogue number
- GC69730
- Brand
- GLPBIO
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il