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Chemical structure of PHGDH-IN-3

GC69701

PHGDH-IN-3

Also known as 4-[(3-acetylphenyl)sulfamoyl]-N-[4-(3-fluorophenyl)-1,3-thiazol-2-yl]benzamide

PHGDH-IN-3 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor with oral activity· It inhibits PHGDH with an IC50 value of 2·8 μM and can be used for cancer research

ChemicalCAS2893778-31-7MW495.55FormulaC24H18FN3O4S2
CAS number
2893778-31-7
Molecular weight
495.55
Formula
C24H18FN3O4S2
Solubility
DMSO ： 100 mg/mL (201·80 mM; ultrasonic and warming and heat to 70°C)
InChIKey
VUAMLKVINZWIJR-UHFFFAOYSA-N
Catalogue number
GC69701
Brand
GLPBIO
Computed properties PubChem CID 166638116 · XLogP 4.1 · TPSA 142 Ų · H-bond donors 2
XLogP
4.1
TPSA
142 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
7
Heavy atoms
34

SMILES CC(=O)C1=CC(=CC=C1)NS(=O)(=O)C2=CC=C(C=C2)C(=O)NC3=NC(=CS3)C4=CC(=CC=C4)F

Computed descriptors from PubChem (CID 166638116), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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