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Chemical structure of Pan KRas-IN-1

GC69653

Pan KRas-IN-1

Also known as (3R)-1-[7-(8-ethyl-7-fluoro-3-hydroxynaphthalen-1-yl)-8-fluoro-2-[[(2R,8S)-2-fluoro-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methoxy]pyrido[4,3-d]pyrimidin-4-yl]-3-methylpiperidin-3-ol

Pan KRas-IN-1 is a pan-KRas inhibitor that can be used for studying cancer resistance to KRas G12C inhibitors

ChemicalCAS2791263-84-6MW607.67FormulaC33H36F3N5O3
CAS number
2791263-84-6
Molecular weight
607.67
Formula
C33H36F3N5O3
Solubility
DMSO ： 100 mg/mL (164·56 mM; Need ultrasonic)
InChIKey
RZYWNBKMTZABBP-PAXFXPPDSA-N
Catalogue number
GC69653
Brand
GLPBIO
Computed properties PubChem CID 164535036 · XLogP 5.8 · TPSA 94.8 Ų · H-bond donors 2
XLogP
5.8
TPSA
94.8 Ų
H-bond donors
2
H-bond acceptors
11
Rotatable bonds
6
Heavy atoms
44

SMILES CCC1=C(C=CC2=CC(=CC(=C21)C3=NC=C4C(=C3F)N=C(N=C4N5CCC[C@@](C5)(C)O)OC[C@@]67CCCN6C[C@@H](C7)F)O)F

Computed descriptors from PubChem (CID 164535036), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.