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Chemical structure of NT219

GC69599

NT219

Also known as (E)-3-(2-bromo-3,4-dihydroxyphenyl)-N-[(3,4,5-trihydroxyphenyl)methyl]prop-2-enethioamide

NT219 is an effective dual inhibitor of insulin receptor substrate 1/2 (IRS1/2) and STAT3· IRS1/2 and STAT3 are major signaling pathways regulated by various oncogenes· NT219 affects the degradation of IRS1/2 and inhibits the phosphorylation of STAT3· NT219 has potential for researching cancer diseases

ChemicalCAS1198078-60-2MW412.26FormulaC16H14BrNO5S
CAS number
1198078-60-2
Molecular weight
412.26
Formula
C16H14BrNO5S
Solubility
DMSO ： ≥ 100 mg/mL (242·57 mM)
InChIKey
XDDQKKXXQHUUHJ-DUXPYHPUSA-N
Catalogue number
GC69599
Brand
GLPBIO
Computed properties PubChem CID 135914977 · XLogP 2.6 · TPSA 145 Ų · H-bond donors 6
XLogP
2.6
TPSA
145 Ų
H-bond donors
6
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
24

SMILES C1=CC(=C(C(=C1/C=C/C(=S)NCC2=CC(=C(C(=C2)O)O)O)Br)O)O

Computed descriptors from PubChem (CID 135914977), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.