GC69596
NSC689857
Also known as 1-adamantylmethyl 4-[(2,5-dihydroxyphenyl)methylamino]benzoate
NSC689857 is an effective inhibitor of EGFR and SCFSKP2, with an IC50 of 36 μM against Skp2-Cks1· NSC689857 can inhibit phosphorylation of p27 (IC50=30 μM)· NSC689857 exhibits varying activity in different types of cancer, with higher resistance activity against leukemia cell lines compared to other cancer cells
ChemicalCAS241127-79-7MW407.5FormulaC25H29NO4
- CAS number
- 241127-79-7
- Molecular weight
- 407.5
- Formula
- C25H29NO4
- Solubility
- DMSO ： 100 mg/mL (245·40 mM; Need ultrasonic)
- InChIKey
- MXKHJVTZHIIIMQ-UHFFFAOYSA-N
- Catalogue number
- GC69596
- Brand
- GLPBIO
Computed properties PubChem CID 391131 · XLogP 5.4 · TPSA 78.8 Ų · H-bond donors 3
- XLogP
- 5.4
- TPSA
- 78.8 Ų
- H-bond donors
- 3
- H-bond acceptors
- 5
- Rotatable bonds
- 7
- Heavy atoms
- 30
SMILES C1C2CC3CC1CC(C2)(C3)COC(=O)C4=CC=C(C=C4)NCC5=C(C=CC(=C5)O)O
Computed descriptors from PubChem (CID 391131), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il