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Chemical structure of NOTA-AE105

GC69588

NOTA-AE105

Also known as (3S)-3-[[2-[4,7-bis(carboxymethyl)-1,4,7-triazonan-1-yl]acetyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-hydroxyethyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-cyclohexyl-1-oxopropan-2-yl]amino]-4-oxobutanoic acid

NOTA-AE105 is a PET ligand for urokinase-type plasminogen activator receptor (uPAR), which can be radiolabeled with 64Cu and 68Ga· The images of 68Ga-NOTA-AE105 and 64Cu-NOTA-AE105 have high contrast and clear tumor delineation

ChemicalCAS1820563-84-5MW1511.68FormulaC72H102N16O20
CAS number
1820563-84-5
Molecular weight
1511.68
Formula
C72H102N16O20
Solubility
DMSO ： 83·33 mg/mL (55·12 mM; Need ultrasonic)
InChIKey
QYDKPVWTZOEIPR-WKDKGDAESA-N
Catalogue number
GC69588
Brand
GLPBIO
Computed properties PubChem CID 168355625 · XLogP -5.8 · TPSA 562 Ų · H-bond donors 19
XLogP
-5.8
TPSA
562 Ų
H-bond donors
19
H-bond acceptors
24
Rotatable bonds
42
Heavy atoms
108

SMILES CC(C)C[C@@H](C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CO)C(=O)O)NC(=O)[C@H](CC3=CC=C(C=C3)O)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](CO)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@H](CC5CCCCC5)NC(=O)[C@H](CC(=O)O)NC(=O)CN6CCN(CCN(CC6)CC(=O)O)CC(=O)O

Computed descriptors from PubChem (CID 168355625), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.