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Chemical structure of NFAT Inhibitor-2

GC69553

NFAT Inhibitor-2

Also known as 4-fluoro-N-(3-fluoro-4-methylphenyl)-3-[(4-methoxyphenyl)methylsulfamoyl]benzamide

NFAT Inhibitor-2 is an effective calcineurin NFAT signaling inhibitor· Calcineurin is a serine/threonine protein phosphatase regulated by Ca2+ and calmodulin· NFAT Inhibitor-2 has potential in researching inflammatory diseases, autoimmune diseases, cardiovascular diseases, neurodegenerative diseases, uncontrolled cell proliferation and/or differentiation disorders, angiogenesis-related diseases, allergies, allergic reactions and hair loss (information taken from patent WO2016207212A1 compound 17)

ChemicalCAS422546-87-0MW446.47FormulaC22H20F2N2O4S
CAS number
422546-87-0
Molecular weight
446.47
Formula
C22H20F2N2O4S
Solubility
DMSO ： 125 mg/mL (279·97 mM; Need ultrasonic)
InChIKey
UILNVCFXMNSVLA-UHFFFAOYSA-N
Catalogue number
GC69553
Brand
GLPBIO
Computed properties PubChem CID 15995931 · XLogP 3.8 · TPSA 92.9 Ų · H-bond donors 2
XLogP
3.8
TPSA
92.9 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
31

SMILES CC1=C(C=C(C=C1)NC(=O)C2=CC(=C(C=C2)F)S(=O)(=O)NCC3=CC=C(C=C3)OC)F

Computed descriptors from PubChem (CID 15995931), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.