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Chemical structure of NFATc1-IN-1

GC69552

NFATc1-IN-1

Also known as 5-fluoro-N-(2-fluoro-4-iodophenyl)-2-hydroxybenzamide

NFATc1-IN-1 (compound A04) is an effective inhibitor of RANKL-induced osteoclast formation, with an IC50 of 1·57 μM· NFATc1-IN-1 displays anti-osteoclastogenic activity by reducing RANKL-induced NFATc1 nuclear translocation· It can be used for research on bone diseases

ChemicalCAS1912422-56-0MW375.11FormulaC13H8F2INO2
CAS number
1912422-56-0
Molecular weight
375.11
Formula
C13H8F2INO2
Solubility
DMSO ： 125 mg/mL (333·24 mM; Need ultrasonic)
InChIKey
IGRCFOGPIJEESA-UHFFFAOYSA-N
Catalogue number
GC69552
Brand
GLPBIO
Computed properties PubChem CID 127043724 · XLogP 3.8 · TPSA 49.3 Ų · H-bond donors 2
XLogP
3.8
TPSA
49.3 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
2
Heavy atoms
19

SMILES C1=CC(=C(C=C1F)C(=O)NC2=C(C=C(C=C2)I)F)O

Computed descriptors from PubChem (CID 127043724), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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