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Chemical structure of ML-SA5

GC69478

ML-SA5

Also known as 1-N-(3-chloro-2-piperidin-1-ylphenyl)-4-N,4-N-dimethylbenzene-1,4-disulfonamide

ML-SA5 is a potent TRPML1 cation channel agonist that can activate the entire intracellular TRPML1 (ML1) current in DMD muscle cells, with an EC50 value of 285 nM, which is more effective than ML-SA1· ML-SA5 has anti-cancer activity and can inhibit tumor growth

ChemicalCAS2418670-70-7MW457.99FormulaC19H24ClN3O4S2
CAS number
2418670-70-7
Molecular weight
457.99
Formula
C19H24ClN3O4S2
Solubility
DMSO : 125 mg/mL (272·93 mM; Need ultrasonic)
InChIKey
YPPWKTIVYUTTEH-UHFFFAOYSA-N
Catalogue number
GC69478
Brand
GLPBIO
Computed properties PubChem CID 154578372 · XLogP 3.2 · TPSA 104 Ų · H-bond donors 1
XLogP
3.2
TPSA
104 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
29

SMILES CN(C)S(=O)(=O)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=CC=C2)Cl)N3CCCCC3

Computed descriptors from PubChem (CID 154578372), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
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