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Chemical structure of Mitochondria degrader-1

GC69469

Mitochondria degrader-1

Also known as (2R)-2-acetamido-3-[[2-amino-9-[(4-fluorophenyl)methyl]-6-oxo-1H-purin-8-yl]sulfanyl]-N-[2-[2-[2-[2-[2-(6-chlorohexoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl]propanamide

Mitochondria degrader-1 (Example 5) is an effective mitochondria degradation agent· Mitochondria degrader-1 induces the degradation of damaged mitochondria through autophagy mechanism· Mitochondria degrader-1 can be used for research on neurodegenerative diseases, cancer, inflammatory diseases, age-related diseases, metabolic diseases, mitochondrial diseases or Down syndrome

ChemicalCAS2241669-05-4MW758.3FormulaC33H49ClFN7O8S
CAS number
2241669-05-4
Molecular weight
758.3
Formula
C33H49ClFN7O8S
Solubility
DMSO ： 100 mg/mL (131·87 mM; Need ultrasonic)
InChIKey
JIUOEUKVQTVYRY-MHZLTWQESA-N
Catalogue number
GC69469
Brand
GLPBIO
Computed properties PubChem CID 142408984 · XLogP 1.4 · TPSA 215 Ų · H-bond donors 4
XLogP
1.4
TPSA
215 Ų
H-bond donors
4
H-bond acceptors
12
Rotatable bonds
28
Heavy atoms
51

SMILES CC(=O)N[C@@H](CSC1=NC2=C(N1CC3=CC=C(C=C3)F)N=C(NC2=O)N)C(=O)NCCOCCOCCOCCOCCOCCCCCCCl

Computed descriptors from PubChem (CID 142408984), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.