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Chemical structure of MDM2-p53-IN-16

GC69444

MDM2-p53-IN-16

Also known as methyl (2S)-4-methyl-2-[[(2S)-2-[[2-oxo-2-(2-phenyl-1H-indol-3-yl)acetyl]amino]-3-phenylpropanoyl]amino]pentanoate

MDM2-p53-IN-16 is a MDM2-p53 complex inhibitor with an IC50 value of 4·3 nM for dissociating the human MDM2-p532 complex· It can reactivate p53 and induce apoptosis and cell cycle arrest in glioblastoma multiforme (GBM) cells· MDM2-p53-IN-16 can be used for cancer research purposes

ChemicalCAS1917350-09-4MW539.62FormulaC32H33N3O5
CAS number
1917350-09-4
Molecular weight
539.62
Formula
C32H33N3O5
Solubility
DMSO ： 100 mg/mL (185·32 mM; Need ultrasonic)
InChIKey
ANEVZIOZUQXCFC-UIOOFZCWSA-N
Catalogue number
GC69444
Brand
GLPBIO
Computed properties PubChem CID 132545406 · XLogP 5.8 · TPSA 117 Ų · H-bond donors 3
XLogP
5.8
TPSA
117 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
12
Heavy atoms
40

SMILES CC(C)C[C@@H](C(=O)OC)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C(=O)C2=C(NC3=CC=CC=C32)C4=CC=CC=C4

Computed descriptors from PubChem (CID 132545406), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.