GC69315
JMS-053
Also known as 7-imino-2-phenylthieno[3,2-c]pyridine-4,6-dione
JMS-053 is an effective, selective, and reversible inhibitor of PTP4A· It inhibits PTP4A1, PTP4A2, PTP4A3, CDC25B and DUSP3 with IC50 values of 29·1 nM, 48·0 nM, 34·7 nM, 92·6 nM and 207·6 nM respectively· JMS-053 can inhibit cancer cell migration and spheroid growth while reducing the growth of ovarian tumors in vivo
ChemicalCAS1954650-11-3MW256.28FormulaC13H8N2O2S
- CAS number
- 1954650-11-3
- Molecular weight
- 256.28
- Formula
- C13H8N2O2S
- Solubility
- DMSO ： 10 mg/mL (39·02 mM; ultrasonic and warming and heat to 60°C)
- InChIKey
- CQHAROORCYWRRH-UHFFFAOYSA-N
- Catalogue number
- GC69315
- Brand
- GLPBIO
Computed properties PubChem CID 124141953 · XLogP 2.4 · TPSA 98.3 Ų · H-bond donors 2
- XLogP
- 2.4
- TPSA
- 98.3 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Rotatable bonds
- 1
- Heavy atoms
- 18
SMILES C1=CC=C(C=C1)C2=CC3=C(S2)C(=N)C(=O)NC3=O
Computed descriptors from PubChem (CID 124141953), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il