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Chemical structure of IST5-002

GC69300

IST5-002

Also known as [(2R,3S,4R,5R)-5-[6-(benzylamino)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate

IST5-002 is an effective inhibitor of Stat5a/b, selectively inhibiting the transcriptional activity of Stat5a/b with IC50 values of 1·5 μM (Stat5a) and 3·5 μM (Stat5b)· IST5-002 induces apoptosis and death in prostate cancer cells and chronic myeloid leukemia (CML) cells· IST5-002 can be used for research on prostate cancer and CML

ChemicalCAS13484-66-7MW437.34FormulaC17H20N5O7P
CAS number
13484-66-7
Molecular weight
437.34
Formula
C17H20N5O7P
Solubility
H2O ： 125 mg/mL (285·82 mM; Need ultrasonic)
InChIKey
DWVANBHPEPSMOV-LSCFUAHRSA-N
Catalogue number
GC69300
Brand
GLPBIO
Computed properties PubChem CID 59310 · XLogP -1.4 · TPSA 172 Ų · H-bond donors 5
XLogP
-1.4
TPSA
172 Ų
H-bond donors
5
H-bond acceptors
11
Rotatable bonds
7
Heavy atoms
30

SMILES C1=CC=C(C=C1)CNC2=C3C(=NC=N2)N(C=N3)[C@H]4[C@@H]([C@@H]([C@H](O4)COP(=O)(O)O)O)O

Computed descriptors from PubChem (CID 59310), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.