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Chemical structure of GSK3-IN-3

GC69195

GSK3-IN-3

Also known as N'-dodecanoyl-1-ethyl-4-hydroxy-2-oxoquinoline-3-carbohydrazide

GSK3-IN-3 is a mitophagy inducer that can induce Parkin-dependent mitochondrial autophagy· It is also a GSK-3 inhibitor with an IC50 value of 3·01 μM· GSK3-IN-3 has non-ATP and non-substrate competitive properties and has neuroprotective effects on 6-OHDA

ChemicalCAS331963-27-0MW429.55FormulaC24H35N3O4
CAS number
331963-27-0
Molecular weight
429.55
Formula
C24H35N3O4
Solubility
DMSO : 4·17 mg/mL (9·71 mM; ultrasonic and warming and heat to 60°C)
InChIKey
MHKIYMMTEMNCFE-UHFFFAOYSA-N
Catalogue number
GC69195
Brand
GLPBIO
Computed properties PubChem CID 54687085 · XLogP 6.5 · TPSA 98.7 Ų · H-bond donors 3
XLogP
6.5
TPSA
98.7 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
12
Heavy atoms
31

SMILES CCCCCCCCCCCC(=O)NNC(=O)C1=C(C2=CC=CC=C2N(C1=O)CC)O

Computed descriptors from PubChem (CID 54687085), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.