
GC69144
Galectin-3 antagonist 1
Also known as [(2R,3S,4S,5S,6R)-5-hydroxy-6-(hydroxymethyl)-2-methoxy-4-(4-methylbenzoyl)oxyoxan-3-yl] 4-chloro-2-nitrobenzoate
Galectin-3 antagonist 1 (compound 15) is an effective and selective Galectin-3 (Gal-3) antagonist with a Kd value of 5·3 μM· Additionally, Galectin-3 antagonist 1 binds to multiple Galectins with Kd values of 250 μM (GAl-4N), 18 μM (Gal-4C), and 450 μM (Gal-8C)
ChemicalCAS2921603-03-2MW495.86FormulaC22H22ClNO10
- CAS number
- 2921603-03-2
- Molecular weight
- 495.86
- Formula
- C22H22ClNO10
- Solubility
- DMSO : 100 mg/mL (201·67 mM; Need ultrasonic)
- InChIKey
- FSBFERQGFVBNEJ-NOYKIMNZSA-N
- Catalogue number
- GC69144
- Brand
- GLPBIO
Computed properties PubChem CID 164513432 · XLogP 3.2 · TPSA 157 Ų · H-bond donors 2
- XLogP
- 3.2
- TPSA
- 157 Ų
- H-bond donors
- 2
- H-bond acceptors
- 10
- Rotatable bonds
- 8
- Heavy atoms
- 34
SMILES CC1=CC=C(C=C1)C(=O)O[C@H]2[C@H]([C@H](O[C@H]([C@H]2OC(=O)C3=C(C=C(C=C3)Cl)[N+](=O)[O-])OC)CO)O
Computed descriptors from PubChem (CID 164513432), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
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- Pricing
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- Documents
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