Loading...
Chemical structure of FPR2 agonist 2

GC69130

FPR2 agonist 2

Also known as 1-[(2S)-3-(4-cyanophenyl)-1-(5-fluoro-2,3-dihydroindol-1-yl)-1-oxopropan-2-yl]-3-(4-fluorophenyl)urea

FPR2 agonist 2 is an effective FPR2 agonist that can penetrate the blood-brain barrier, with an EC50 value of 0·13 µM for h-FPR2· It inhibits the production of pro-inflammatory cytokines, counteracts changes in mitochondrial function, and suppresses caspase-3 activity

ChemicalCAS2829263-20-7MW446.45FormulaC25H20F2N4O2
CAS number
2829263-20-7
Molecular weight
446.45
Formula
C25H20F2N4O2
Solubility
DMSO : 50 mg/mL (111·99 mM; Need ultrasonic)
InChIKey
KCNMTQVKKFREAN-QFIPXVFZSA-N
Catalogue number
GC69130
Brand
GLPBIO
Computed properties PubChem CID 163322252 · XLogP 4 · TPSA 85.2 Ų · H-bond donors 2
XLogP
4
TPSA
85.2 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
5
Heavy atoms
33

SMILES C1CN(C2=C1C=C(C=C2)F)C(=O)[C@H](CC3=CC=C(C=C3)C#N)NC(=O)NC4=CC=C(C=C4)F

Computed descriptors from PubChem (CID 163322252), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.