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Chemical structure of FGFR3-IN-5

GC69106

FGFR3-IN-5

Also known as 6-[1-[1-(3-fluoro-1-prop-2-enoylazetidine-3-carbonyl)piperidin-4-yl]pyrazol-4-yl]-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile

FGFR3-IN-5 is an effective selective inhibitor of FGFR3, with IC50 values of 3, 44, and 289 nM for FGFR3, FGFR2, and FGFR1 respectively· It can be used in cancer research

ChemicalCAS2446664-72-6MW477.49FormulaC24H24FN7O3
CAS number
2446664-72-6
Molecular weight
477.49
Formula
C24H24FN7O3
InChIKey
GUEZCEZQFMVREH-UHFFFAOYSA-N
Catalogue number
GC69106
Brand
GLPBIO
Computed properties PubChem CID 153619578 · XLogP 0.7 · TPSA 109 Ų · H-bond donors 0
XLogP
0.7
TPSA
109 Ų
H-bond donors
0
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
35

SMILES COC1=CC(=CN2C1=C(C=N2)C#N)C3=CN(N=C3)C4CCN(CC4)C(=O)C5(CN(C5)C(=O)C=C)F

Computed descriptors from PubChem (CID 153619578), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.