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Chemical structure of ERCC1-XPF-IN-2

GC69079

ERCC1-XPF-IN-2

Also known as 2-(2,4-dichlorophenyl)-N-[(3,4-dihydroxyphenyl)methyl]acetamide

ERCC1-XPF-IN-2 is an effective inhibitor of the ERCC1-XPF endonuclease with an IC50 value of 0·6 µM· ERCC1-XPF-IN-2 has shown activity in nucleotide excision repair, cisplatin enhancement, and γH2AX assays

ChemicalCAS1808986-37-9MW326.17FormulaC15H13Cl2NO3
CAS number
1808986-37-9
Molecular weight
326.17
Formula
C15H13Cl2NO3
Solubility
DMSO : ≥ 250 mg/mL (766·47 mM)
InChIKey
BKPCQXGBKRAJDW-UHFFFAOYSA-N
Catalogue number
GC69079
Brand
GLPBIO
Computed properties PubChem CID 122189958 · XLogP 3.2 · TPSA 69.6 Ų · H-bond donors 3
XLogP
3.2
TPSA
69.6 Ų
H-bond donors
3
H-bond acceptors
3
Rotatable bonds
4
Heavy atoms
21

SMILES C1=CC(=C(C=C1CNC(=O)CC2=C(C=C(C=C2)Cl)Cl)O)O

Computed descriptors from PubChem (CID 122189958), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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