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Chemical structure of E7090

GC69037

E7090

Also known as 5-[[2-[[4-[1-(2-hydroxyethyl)piperidin-4-yl]benzoyl]amino]-4-pyridinyl]oxy]-6-(2-methoxyethoxy)-N-methylindole-1-carboxamide

E7090 is an effective selective FGFR inhibitor with oral activity, with IC50 values of 0·71 nM, 0·50 nM, 1·2 nM and 120 nM for FGFR1/FGFR2/FGFR3/FGFR4 respectively

ChemicalCAS1622204-21-0MW587.67FormulaC32H37N5O6
CAS number
1622204-21-0
Molecular weight
587.67
Formula
C32H37N5O6
Solubility
DMSO ： 100 mg/mL (170·16 mM; Need ultrasonic)
InChIKey
IBHOLSBDZMIPPT-UHFFFAOYSA-N
Catalogue number
GC69037
Brand
GLPBIO
Computed properties PubChem CID 78323434 · XLogP 3.1 · TPSA 127 Ų · H-bond donors 3
XLogP
3.1
TPSA
127 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
11
Heavy atoms
43

SMILES CNC(=O)N1C=CC2=CC(=C(C=C21)OCCOC)OC3=CC(=NC=C3)NC(=O)C4=CC=C(C=C4)C5CCN(CC5)CCO

Computed descriptors from PubChem (CID 78323434), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.