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Chemical structure of Dentonin

GC68963

Dentonin

Also known as (2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-1-[(2S)-5-amino-2-[[2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxybutanoyl]amino]-3-carboxypropanoyl]amino]-4-methylpentanoyl]amino]-5-oxopentanoyl]amino]-4-carboxybutanoyl]amino]-5-carbamimidamidopentanoyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]-4-oxobutanoyl]amino]-3-carboxypropanoyl]amino]-3-methylpentanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]acetyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]hexanoyl]amino]butanedioic acid

Dentonin (AC-100) is a short peptide fragment derived from MEPE· Dentonin promotes osteogenesis by promoting the adhesion of osteoprogenitor cells and can also promote the survival of immature adherent cells· Dentonin has no significant effect on mature bone-forming cells· Dentonin can be used for research on phosphate homeostasis and bone metabolism

ChemicalCAS400090-20-2MW2538.59FormulaC107H160N30O42
CAS number
400090-20-2
Molecular weight
2538.59
Formula
C107H160N30O42
InChIKey
PRFOXOFIVVOCCT-GRDAUCDVSA-N
Catalogue number
GC68963
Brand
GLPBIO
Computed properties PubChem CID 145722058 · XLogP -18.1 · TPSA 1190 Ų · H-bond donors 38
XLogP
-18.1
TPSA
1190 Ų
H-bond donors
38
H-bond acceptors
45
Rotatable bonds
84
Heavy atoms
179

SMILES CC[C@H](C)[C@@H](C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C(C)O)N

Computed descriptors from PubChem (CID 145722058), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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