GC68903
cRIPGBM chloride
Also known as 3-benzyl-1-[(4-fluorophenyl)methyl]-2-methylbenzo[f]benzimidazol-3-ium-4,9-dione chloride
cRIPGBM chloride is an orally effective pro-apoptotic derivative that can be produced from cancer stem cells (CSC) of glioblastoma multiforme (GBM)· cRIPGBM chloride induces caspase 1-dependent cell apoptosis by targeting receptor-interacting protein kinase 2 (RIPK2) through the formation of RIPK2/caspase 1 complex and inhibition of RIPK2/TAK1 (pro-survival complex) formation· In animal models, cRIPGBM chloride exhibits strong in vivo anti-tumor activity
- CAS number
- 2361988-77-2
- Molecular weight
- 446.9
- Formula
- C26H20ClFN2O2
- Solubility
- DMSO ： 25 mg/mL (55·94 mM; ultrasonic and warming and heat to 60°C)
- InChIKey
- IHNGETPFBJHWFE-UHFFFAOYSA-M
- Catalogue number
- GC68903
- Brand
- GLPBIO
Computed properties PubChem CID 156024495 · TPSA 43 Ų · H-bond donors 0 · H-bond acceptors 4
- TPSA
- 43 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Rotatable bonds
- 4
- Heavy atoms
- 32
SMILES CC1=[N+](C2=C(N1CC3=CC=C(C=C3)F)C(=O)C4=CC=CC=C4C2=O)CC5=CC=CC=C5.[Cl-]
Computed descriptors from PubChem (CID 156024495), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il