GC68857
Cetrelimab
Cetrelimab (JNJ 63723283; JNJ 3283) is a humanized IgG4 monoclonal antibody that targets PD-1· Cetrelimab has a Kd of 1·72 nM for binding to PD-1 (HEK293 cells)· As such, Cetrelimab blocks the interaction between PD-1 and its ligands, PD-L1 and PD-L2 (with IC50 values of 111·7 ng/mL and 138·6 ng/mL, respectively)· Cetrelimab also stimulates peripheral T cells, increases cytokine levels (IFN-gamma, IL-2, TNF-alpha), and inhibits tumor growth in vivo
ChemicalCAS2050478-92-5
- CAS number
- 2050478-92-5
- Molecular weight
- —
- Formula
- —
- Catalogue number
- GC68857
- Brand
- GLPBIO
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il