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Chemical structure of BMS-770767

GC68782

BMS-770767

Also known as 4-[8-(2-chlorophenoxy)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]bicyclo[2.2.1]heptan-1-ol

BMS-770767 is a type 2 diabetes inhibitor of 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1), which is an important enzyme widely expressed in the liver, adipose tissue and other tissues· It plays an important role in metabolic diseases such as diabetes and obesity

ChemicalCAS1875067-34-7MW355.82FormulaC19H18ClN3O2
CAS number
1875067-34-7
Molecular weight
355.82
Formula
C19H18ClN3O2
Solubility
DMSO : 100 mg/mL (281·04 mM; ultrasonic and warming and heat to 80°C)
InChIKey
HNXGIFYHJKEXNA-UHFFFAOYSA-N
Catalogue number
GC68782
Brand
GLPBIO
Computed properties PubChem CID 57809036 · XLogP 4 · TPSA 59.7 Ų · H-bond donors 1
XLogP
4
TPSA
59.7 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
25

SMILES C1CC2(CCC1(C2)C3=NN=C4N3C=CC=C4OC5=CC=CC=C5Cl)O

Computed descriptors from PubChem (CID 57809036), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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